Gaucher disease type 1
Adult: As a long-term enzyme replacement therapy: Initially, 60 units/kg once every 2 weeks via infusion over 60 minutes. Usual dosage range: 15-60 units/kg once every 2 weeks. Dosage is individualised based on the severity of the disease and adjusted according to the achievement and maintenance of therapeutic goals. Patients on imiglucerase therapy: May initiate velaglucerase alfa 2 weeks after the last imiglucerase dose, using the same dose and frequency.
Child: ≥4 years Same as adult dose.
Child: ≥4 years Same as adult dose.